• INHERITED PROSTATE CANCER GENE IDENTIFIED

    Updated: 2012-02-29 19:58:09
    Men who inherit a mutation in the HOXB13 gene have a 10 to 20 times increased risk of developing prostate cancer, according to the study in the January 12, 2012 issue of the New England Journal of Medicine. Finally, the first major gene mutation associated with an increased risk for prostate cancer has been identified. [...]

  • Selenium Supplements May Help or Harm

    Updated: 2012-02-29 03:25:28
    Health News Selenium Supplements May Help or Harm Print E-mail TUESDAY , Feb . 28 HealthDay News While getting the right amount of selenium in your diet can boost your immune function and lower your risk of death , you can get too much of a good thing . Higher-than-normal levels of selenium may contribute to the development of type 2 diabetes , hair loss and certain cancers , a new review of evidence finds . There is a U-shaped relationship between selenium intake and health . As selenium intake goes up from a low value , health improves until the bottom of the U-shaped curve is reached , but then adverse or even toxic effects begin to be seen , said Margaret Rayman , the author of the review of selenium research , and a professor of nutritional medicine at the University of Surrey , in

  • EU cancer death rate expected to fall again

    Updated: 2012-02-29 00:30:00
    Researchers predict that the proportion of the European Union (EU) population that dies from cancer will continue to drop in 2012.

  • HPV testing followed by smear could improve cervical screening

    Updated: 2012-02-29 00:01:00
    Testing for the human papillomavirus (HPV) - a virus most women will encounter at some point in their lives - followed by a smear test if they are HPV positive, provides the most effective approach for cervical screening, new research shows today (Wednesday).

  • Prostate Cancer Tx Up, but in Wrong Group

    Updated: 2012-02-28 20:01:56
    Older men with low-risk prostate cancer received increasingly aggressive treatment over a 10-year period, whereas practices did not change for men most likely to benefit from curative therapy, a study showed.

  • Scientists crack conundrum of how combined chemotherapy destroys pancreatic cancer cells

    Updated: 2012-02-28 15:00:00
    Cancer Research UK scientists have discovered how a combination of two chemotherapy drugs ¿ already showing promise in clinical trials ¿ destroys pancreatic cancer cells, according to research published in Cancer Discovery.

  • Sleeping Pills Linked to Raised Risk of Death Cancer Study

    Updated: 2012-02-28 11:23:31
    , : Health News Sleeping Pills Linked to Raised Risk of Death , Cancer : Study Print E-mail MONDAY , Feb . 27 HealthDay News Prescription sleeping pills may help you get some much needed rest at night , but using them routinely might also make it more likely that you will die or develop certain types of cancer , research . suggests A new study suggests that those who take these medications are four times more likely to die than people who don't take them . What's more , the research shows that sleeping pill use is also associated with a raised risk for certain cancers . The findings appear online Feb . 27 in the journal BMJ Open Sleeping pills linked to these risks included benzodiazepines such as temazepam non-benzodiazepines such as Ambien zolpidem Lunesta eszopiclone and Sonata zaleplon

  • Chemo Brain' May Linger 20 Years After Breast Cancer Treatment

    Updated: 2012-02-28 11:23:31
    Health News Chemo Brain' May Linger 20 Years After Breast Cancer Treatment Print E-mail MONDAY , Feb . 27 HealthDay News Chemo brain , the name given to the mental fog and related memory problems that can occur during and after chemotherapy , may last for two decades after breast cancer treatment , new research suggests . In the new study , 196 women with breast cancer who were treated with chemotherapy roughly 21 years earlier performed worse on tests of their memory , processing speed and other thinking cognitive skills when compared to their counterparts who had never been diagnosed with cancer . Participants had all been treated for breast cancer with a chemotherapy combination that included the drugs cyclophosphamide , methotrexate and 5-fluorouracil between 1976 and 1995. This

  • FDA and Medicare Regulation—Their Role And What Will Happen In the Future – Part Two of a Two Part Post

    Updated: 2012-02-27 20:24:44
    Will the Centers for Medicare & Medicaid Services (CMS) be able to optimize patient care with regard to both on-label and off-label drugs? CMS’, at this time, has not shown itself to be either in favor or against new technology or the introduction of new uses for drugs. They still seem interested in promoting access [...]

  • FDA and Medicare Regulation—Their Role And What Will Happen In the Future – Part One of a Two Part Post

    Updated: 2012-02-25 19:27:35
    Historically, I have been critical of the FDA, especially around the delay of the approval of Provenge. Now, it is time to take a look at the FDA and what I believe the future will be for this agency. I do first need to make it clear that I do believe that the FDA plays [...]

  • In Tougher Economy Fewer Americans Get Colonoscopy

    Updated: 2012-02-25 05:55:07
    , Health News In Tougher Economy , Fewer Americans Get Colonoscopy Print E-mail FRIDAY , Feb . 24 HealthDay News Fewer people opted for potentially lifesaving colonoscopies to screen for colon cancer during the recent economic recession , largely because they couldn't afford to pay high out-of-pocket costs often associated with this test , new research . finds During the recession of December 2007 to June 2009, about 500,000 fewer Americans who had health insurance underwent a screening colonoscopy , compared to the two years before the recession began . The study findings appear in the March issue of Clinical Gastroenterology and Hepatology In difficult economic times , people are more likely to forgo necessary medical services if there are high out-of-pocket costs , said study author Dr

  • No Good Treatment for Men with Chemotherapy Induced Neuropathy

    Updated: 2012-02-24 20:25:06
    One of the common side effects reported from chemotherapy with Taxotere is neuropathy. In the trial used to receive FDA approval, TAX 327 which had 332 patients. In that trial the following percentage of men reported incidents of neuropathy: Neuropathy Sensory- Nerve damage causing tingling or pain, usually in feet or hands: Any Grade- 30.4% [...]

  • Why Cancer Symptoms May Elude M.D

    Updated: 2012-02-24 17:47:40
    . Health News Why Cancer Symptoms May Elude . M.D Print E-mail FRIDAY , Feb . 24 HealthDay News Diagnosing cancer is more difficult in certain groups of patients , according to a British . study Researchers analyzed data gathered from more than 41,000 patients with 24 types of cancer who were treated in 158 hospitals across England . They found that 77 percent of those who saw their family doctor about suspicious symptoms were referred to a hospital after only one or two . consultations However , the study found that women , young people , non-white patients and patients with less common cancers were more likely to see their family doctor three or more times before they were referred to a . hospital The researchers identified large differences in the promptness of family doctors in England

  • Study reveals variation in how quickly doctors refer suspected cancer patients

    Updated: 2012-02-24 10:37:00
    The speed GPs refer people with suspected cancer to hospital depends on the patient's age, sex, ethnicity and the type of cancer, according to new research.

  • Denosumab (Xgeva) Benefits Greatest in Men with Rapid PSA Kinetics

    Updated: 2012-02-23 19:33:50
    Denosumab (Xgeva), the recently approved and only therapy that prolongs bone metastasis-free survival in men with non-metastatic castrate-resistant prostate cancer (CRPC) who are at high risk for the spread of prostate cancer metastasis to bone seems to work best in men with very rapid prostate specific antigen (PSA) kinetics. The large 1,432 man, placebo controlled, [...]

  • Scientists uncover how a 'master regulator' protein contributes to cancer spread

    Updated: 2012-02-23 10:56:00
    New detail about how a protein called mTOR controls the spread of cancer has been uncovered by US scientists.

  • Study uncovers types of ovarian cancer linked to endometriosis

    Updated: 2012-02-21 18:06:00
    The link between endometriosis and a slightly increased risk of ovarian cancer has been confirmed in a US study.

  • Drug combination domino effect destroys pancreatic cancer cells

    Updated: 2012-02-20 14:01:00
    Cancer Research UK scientists have revealed how a combination of two very different drugs - currently being tested in clinical trials - amplifies the destruction of pancreatic cancer cells, according to research published in the Journal of Experimental Medicine, today.

  • Charities slam tobacco packaging report

    Updated: 2012-02-20 13:27:00
    Anti-smoking campaigners have criticised claims that plain packaging for cigarettes will have no public health benefit.

  • Cancer Research UK welcomes prostate cancer drug approval in Wales

    Updated: 2012-02-20 11:24:00
    Cancer Research UK welcomes the news that the All Wales Medicines Strategy Group (AWMSG) has made prostate cancer drug abiraterone available on the NHS, paving the way for NICE to make a positive ruling when they publish their final guidance in May.

  • Lab Notes: Stroke Recovery Loves Company

    Updated: 2012-02-17 21:01:00
    Topping this week's Lab Notes, mice showed more extensive neuron loss when they were housed alone after induced strokes, suggesting that lack of companionship may interfere with stroke recovery.

  • Ben Venue Plant Trouble Hits One More Onco Drug

    Updated: 2012-02-17 20:33:42
    Manufacturing problems at Bedford Laboratories' now-closed Ben Venue manufacturing plant have forced the recall of another important cancer drug, cytarabine.

  • Researchers close in on new way to treat aggressive bowel cancers

    Updated: 2012-02-17 18:37:00
    Targeting a 'previously unappreciated' protein could lead to a treatment for aggressive bowel cancer, US researchers have found.

  • Scan predicts success of radiotherapy for neuroendocrine tumours

    Updated: 2012-02-17 17:48:00
    Patients with advanced neuroendocrine tumours could be given a magnetic resonance imaging (MRI) scan to predict their response to treatment, say UK scientists.

  • Leading UK model agencies sign up to 'No Sunbed' policy

    Updated: 2012-02-17 00:01:00
    Ahead of London Fashion Week, leading model agencies sign groundbreaking 'No Sunbed' policy agreement as part of Cancer Research UK's R UV UGLY? campaign after warnings on health and appearance

  • Oral Nutrition Supplements Give Little Help to Cancer Patients

    Updated: 2012-02-16 19:47:44
    Malnourished cancer patients had some improvement in quality of life but did not live longer when they received oral nutrition supplements, a meta-analysis showed.

  • Scientists find rare childhood kidney cancer gene fault

    Updated: 2012-02-16 17:57:00
    Faults in gene called DIS3L2 are linked to an increased risk of a form of childhood kidney cancer, scientists have discovered.

  • Can Photo Dynamic Therapy Be On The Horizon?

    Updated: 2012-02-16 16:37:04
    Over the years there has been discussion about using Photo Dynamic Therapy to destroy internal tumors, including prostate cancer tumors. Until now it has only been a hope since there is no way to monitor the amount of light that is actually administered to an internal tumor. We currently use laser light in combination with [...]

  • Patients need more guidance on chemo web information

    Updated: 2012-02-15 00:01:00
    Doctors and nurses may be underestimating the value placed on internet chemotherapy information by cancer patients and missing out on opportunities to discuss this information with them, new research finds today.

  • Hundreds more breast cancer patients should be tested for BRCA1 gene

    Updated: 2012-02-15 00:01:00
    Leading breast cancer experts are calling for women under 50 who are diagnosed with triple-negative (TN) breast cancer to be offered testing for faults in the BRCA1 gene, according to a report published in the British Journal of Cancer today.

  • CBT is effective for menopausal symptoms after breast cancer treatment

    Updated: 2012-02-15 00:01:00
    Research funded by Cancer Research UK suggests that cognitive behavioural therapy (CBT) can help women who have had breast cancer treatment manage the common side-effects of hot flushes and night sweats.

  • More From ASCO – Too Many Patients with Advanced Prostate Cancer Do Not Get Required Treatment

    Updated: 2012-02-14 20:36:16
    Abstract No:101 at the recent ASCO Conference It is sad, but it is true, a subset of men presenting with advanced prostate cancer never receive proper therapy. This can be attributed to a variety of factors including poor functional status, co-morbidities, and patient preference. The researchers sought to determine the prevalence, and characteristics, of this [...]

  • Scientists reveal best imaging technique for ovarian cancer

    Updated: 2012-02-14 00:26:00
    Cancer Research UK-funded scientists have determined that a magnetic resonance imaging (MRI) technique, which measures the movement of water molecules within the tumour, may be the best way to monitor how women with late-stage ovarian cancer are responding to treatment. The study is published in the journal Radiology today.

  • Famous Harrys join host of celebrities to support Help Harry Help Others

    Updated: 2012-02-10 14:42:00
    Famous Harrys have united to launch a fundraising campaign for Help Harry Help Others, the campaign started by the inspirational Harry Moseley who died of a brain tumour in October 2011, aged just 11.

  • Dr. Philip Kantoff Supports the Need For Personalized Medicine for Men with Advanced Prostate Cancer

    Updated: 2012-02-08 19:32:31
    At the 2012 Genitourinary Cancers Symposium ASCO conference, Dr. Philip Kantoff (Dana-Farber Cancer Institute, Harvard Medical School Boston, MA) suggested taking a personalized approach to the individualized treatment plan for all men suffering from advanced prostate cancer. Dr. Kantoff said, “Few patients with advanced prostate cancer are currently cured with ADT (but anecdotally, long-term survival [...]

  • FDA Panel Turns Down Bone Drug in Prostate Ca

    Updated: 2012-02-08 19:24:29
    WASHINGTON -- An FDA panel has voted 12-1 against expanding the indication for Amgen's denosumab (Xgeva) to prevent the spread of prostate cancer to the bones in men with a high-risk form of the disease.

  • US scientists show how immune system 'prunes' tumours

    Updated: 2012-02-08 18:08:00
    Laboratory research by US scientists has shown for the first time how the body's immune system shapes how a tumour grows.

  • Will the FDA Approve Xgeva – It is “Up In The Air”

    Updated: 2012-02-07 18:56:24
    Prior to the formal review, the FDA has raised questions about the ultimate approval of Amgen’s Xgeva (denosumab) for men with metastatic, advanced prostate cancer who have not yet developed metastasized to the bone. Xgeva has been shown to delay tumors spreading to bones, but it does not extend life, the holy grail of the [...]

  • Change4Life warns of cancer risk from drinking 'a little too much'

    Updated: 2012-02-07 16:12:00
    People are at risk from serious illness including cancer, heart disease and stroke if they drink just slightly more than they should, Andrew Lansley has warned.

  • Promising breast cancer prevention drug 'weakens bones'

    Updated: 2012-02-07 13:41:00
    The drug exemestane, which is used to treat breast cancer and is also in trials to prevent the disease developing in postmenopausal women, significantly worsens age-related bone loss, according to a study from Canada.

  • Benefit of Bone Drug in Prostate Cancer in Doubt

    Updated: 2012-02-07 13:00:00
    WASHINGTON -- FDA reviewers have questioned whether expanding the indication for Amgen's denosumab (Xgeva) to prevent the spread of prostate cancer to the bones would provide much added benefit.

  • Video Interview Explaining That Provenge Actually Has A 7.8 Month Life Extension Advantage

    Updated: 2012-02-06 20:52:06
    As a follow up to my last post about the three posters that appeared at the American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium meeting I am going to share with you a video interview with Dr. Chadi Nabhan. Dr. Nabhan talks about his presentation about the phase III results of the Provenge IMPACT [...]

  • Abbreviated Radiotherapy Shows Promise in Prostate Ca

    Updated: 2012-02-05 17:13:54
    SAN FRANCISCO -- Dramatically condensing radiation treatment for early prostate cancer into just five fractions produces good results without much toxicity, an early-phase study suggested.

  • Vaccine Eyed for Early-Stage Prostate Ca

    Updated: 2012-02-04 23:03:35
    SAN FRANCISCO -- The immunotherapy agent sipuleucel-T (Provenge) appears safe for use earlier in prostate cancer, researchers found.

  • Bone Drug Slows Mets in Aggressive Prostate Ca

    Updated: 2012-02-04 22:57:55
    SAN FRANCISCO -- Denosumab (Xgeva) delays onset of bone metastases for even the highest-risk prostate cancer patients, researchers found.

  • Sleep Troubles May Up Prostate Cancer Risk

    Updated: 2012-02-03 22:04:02
    SAN FRANCISCO -- Severe sleep problems suggestive of insomnia are associated with an increased risk of prostate cancer among older men, researchers found.

  • Metastatic Prostate Cancer Often Untreated

    Updated: 2012-02-03 21:09:14
    SAN FRANCISCO — Prostate cancer that has already spread to other organs at time of diagnosis is left untreated in 11% of cases, and demographics make a difference in the decision, researchers reported.

  • Startling reduction in Heart Attack Deaths in Wartime Norway

    Updated: 2012-02-02 21:39:58
    This is a fascinating case study that brings relevant evidence pertinent to heart disease directly to the forefront. It should serve as a convincing argument about why people suffer from heart attacks, and also act as a guide on how to avoid them, which is the primary reason that the ‘Lower Blood Pressure’ website exists. [...]

  • Most Common Tx for Prostate Ca Not Best Value

    Updated: 2012-02-02 19:53:19
    SAN FRANCISCO -- External beam radiation is the most toxic and expensive among common prostate cancer treatments over the long-term, a national registry study suggested.

  • Proton Beam No Better than IMRT for Prostate Cancer

    Updated: 2012-02-02 18:48:22
    SAN FRANCISCO -- For localized prostate cancer, proton beam radiation offers no advantage in minimizing recurrences or side effects, study results suggested.

  • Prostate cancer NICE decision 'makes no sense'

    Updated: 2012-02-02 00:01:00
    Cancer Research UK is urging a solution to the impasse over the advanced prostate cancer drug abiraterone, which has been turned down by NICE.

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